Marijuana, particularly known for its high THC content, is widely consumed around the world. However, the effects of marijuana on the brain and body are not yet fully understood, and scientists continue to gain new insights. A new study published in the Molecular Psychiatry journal reveals that high-potency marijuana use can create permanent and significant changes in DNA. These changes particularly manifest differently in individuals who experience psychosis.
The research can help us better understand how marijuana contributes to the development of psychosis. THC, known as the most active component of marijuana, has significantly increased in marijuana products in both the UK and the US in recent years. In some US states like Colorado, marijuana products can contain THC levels up to 90%.
Effects of DNA Methylation on Marijuana Use
Researchers have studied how marijuana affects DNA methylation, a process that controls gene expression and regulates gene activity. It has been found that high-potency marijuana use leads to methylation changes in genes that manage energy and immune system functions. These changes were noted to be different in individuals who have experienced psychosis. These findings could be an important step in understanding the marks left by marijuana use on genes and how these changes could trigger psychosis.
Future research is expected to explore whether DNA changes associated with marijuana use could be potential biomarkers. These studies will help us better understand the long-term health effects of marijuana use and could provide crucial information in preventing serious health issues like psychosis.